Are there host factors that contribute to the risk of infection? Additional details on clinical presentations What common complications are associated with infection with this pathogen? What alternative therapies are available? Capsule serotypes associated with neonatal disease including Ia, III, and V being evaluated for inclusion in multivalent conjugate vaccines also account for a large proportion of serotypes associated with adult disease. Among those with a documented source, skin and soft tissue infections are the most important clinical syndromes associated with invasive GBS infections in adults, including cellulitis, infected decubitus ulcers, and diabetic foot ulcers.
Most cases occur in postpartum women, elderly adults, or adults with significant underlying diseases.
Group B Streptococcus Bacteremia in Nonpregnant Adults
Infections associated with intravenous and arterial catheters and devices including pacemaker wires and vascular graft material have been reported. Serious GBS infections, such as bacteremia, sepsis, and pneumonia, can be deadly for adults. Approximately one-third of adult GBS meningitis cases have a fatal outcome, and survivors may be left with permanent neurologic sequelae, such as deafness. The latter occur exclusively in patients with diabetes and are frequently complicated by osteomyelitis. Some individuals, such as older adults and those with chronic health conditions, can develop a more serious infection from group B strep.